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Issue 736
October 12
 
 
 
 
 
Traditional TV
72% of patients learn of DTP programs via TV
Source: Health Union

Here at the Klick Wire we came from digital and we believe in those channels for most patient tasks. However, you have to trust the data when you see them. If you're selling in TV for 2027, this is for you. If not, the HCP stat may be useful.

Health Union surveyed 1,398 patients and 63 HCPs about Direct-to-patient perceptions and usage. The HCPs had a focus on endocrinologists because of the strong alignment of DTP with GLP-1s. 

As Seen on TV
 

TV is the top way that patients hear about DTP programs. Unless they actually use the programs, then 69% say they heard about it from their doctor.

healthunion-dtp-learn-560
Chart created with data from Health Union source, the HCP stat not in public PDF
 

For the digital afficionados, notice that social media is the top non-TV channel and may be even more effective for more rare conditions (speculation -Ed.).

DTP Not About to Become Top Sales Channel
 

While DTP has its place in the healthcare ecosystem, insurance still handles the vast majority of drug sales. Outside of GLP-1s only 4% of patients have used the programs (or average of everyone including them, it's hard to tell from the report wording).

healthunion-dtp-usage-560
Image adapted for email from Health Union source
 
HCPs Will Recommend Your DTP Program (Maybe)
 

HCPs are way more positive toward DTP programs than might be initially assumed. Here is where we have to remember the selection bias in the small HCP survey. There are mainly GPs and Endos in the mix but even so 80% usage is impressive.

healthunion-dtp-hcp-560
Chart created with data from Health Union source
 

Follow this link to pick up the preview report from Health Union then you can get the full report from the company. 

The full report includes data on 14 different programs. It's worth the discussion for anyone thinking of starting their own DTP program.

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Read the full story from Health Union
 
 
 
 
GenAI in Healthcare
64% of Americans use AI, 35% for health questions
Source: Menlo Ventures

A report from Menlo is based on a survey of 5,067 U.S. adults and looks at their use of AI. 

Gemini Nips at ChatGPT's Heels
 

Google Gemini is very close to OpenAI's ChatGPT in this survey. This chart seems to include Google AI Overviews in the Gemini number which explains it's position. 

Gemini’s growth underscores the power of distribution. Google put AI everywhere—inside search, Android, and Workspace—reaching over a billion of consumers who never had to seek it out.

 
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Image adapted for email from Menlo Ventures source
 
25% of Americans Seek Health Answers on AI
 

Here we see a comparison of how many Americans perform a task in general and how many perform it with AI. For example, 71% research health questions and 25% of all Americans use AI to do this.

menlo-ai-health-tasks-560
Image adapted for email from Menlo Ventures source
 
Americans Still Prefer Humans to AI for Many Tasks
 

When it comes to preference, Americans want people first. However, a growing number are beginning to prefer AI, depending on the topic. 

menlo-ai-humansfirst-560
Image adapted for email from Menlo Ventures source
 
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Read the full story from Menlo Ventures
 
 
 
 
GenAI Search
55% of AIO citations are controlled by brand
Source: Klick Wire

Last week we ran a story on 83% of branded searches getting AI overviews (from Ahrefs). In that story we looked at four random drug names that came to mind and found that all of them had AI Overviews.

This piqued our interest. 

The Process
 

We first did a manual test of 25 brands, looking at whether an AI overview appeared, and if it did was it above or below the sponsored results. Again, all of the brand name searches contained AI overviews and 52% (13) of the results were above the sponsored links. 

We then looked at the links found in various placements on the AI overviews.

klick-aio-research-map-key-560
Image adapted for email from Klick Wire source
 

This keyed image was used to describe to the AI where we might find the items we wanted it to detect (AIO existence, above or below the sponsored links, citation destinations, etc.).

The Results
 

It turns out that AI's results were as good as our run-to-run variance manually. So we created a set of agents to review the top 100 drugs by global sales and found the average number of times that the company controlled the content being cited.

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3. 55% of AIO description boxes

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4. 39% of the first descriptive citations

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5. 40% of the second descriptive citations (when they appear, approximately 50% of the time)

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6. 90% of the first sidebar citations

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7. 40% of the second sidebar citations

 

So, for brand name drug searches there are a lot of citations directing back to the company's information. The process is by no means bulletproof yet, and we end up running the scripts manually in Claude, but if anyone wants a demo of how we did this just reply to your copy of the Wire and the author can set you up.

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Read the full story from Klick Wire
 
 
 
Klick Wire Asset_ 1280 x 620_100% (2)
 

Six years of Klick submission data, across more than 40,000 reviews and 110 pharmaceutical clients, show that MLR friction often reflects process design, not regulatory complexity alone.

Examine what changes when regulatory expertise enters content development earlier and how Klick Guardrail™ scales that model across brands and markets.

 
Read the article
 
 
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Healthcare Costs
US healthcare is a negative-sum game
Source: Trilliant

Trilliant's US healthcare industry report for 2026 is extensive at 141 pages. We were struck by how much of the data has already been reported in the Klick Wire for HCP burnout, AI use by physicians, and in PA management. But, some new items do exist.

Trust in Hospitals and Doctors Degraded
 

Americans' trust in institutions has been falling for years generally, and this data is likely brought down by including hospitals with doctors, but still it's low. Keep in mind that this is only the top answer, not top two boxes and that will naturally depress the numbers.

trilliant-2026-trust-560
Image adapted for email from Trilliant source
 

Pharma at 14% tracks. Sorry, fellow pharma marketing kids. 

Costs Up 57% Over 10 Years
 

The main argument in the report is that costs and results in the US healthcare system are not sustainable and we are set for a "negative-sum game" with increasing usage and decreasing funding base.

trilliant-2026-costs-560
Image adapted for email from Trilliant source
 
32% of Prescriptions Rejected by Payers
 

In analysis of payer patterns, 32% of written prescriptions went unpaid by insurance from 2018-2024. This can easily cause other costs in the system as patients need more ER time or physical interventions.

trilliant-2026-rejections-560
Image adapted for email from Trilliant source
 

At 141 pages chock full of data we just can't do this report justice in the Wire. If you're looking for an excellent, if critical, overview of the US healthcare system this is for you.

—
Read the full story from Trilliant
 
 
 
 
Influencers
34% of health influencer posts on medical topics
Source: Pew Research

Pew Research has data on health influencers and looks at what topics they focus on. Most of the content is on healthy living but 34% is on actual medical content.

pewresearch-influencers-topics-560
Image adapted for email from Pew Research source
 

The top topics highlight the younger demographic that tunes in for medical podcasts.

pewresearch-influencers-topics-ranked-560
Chart created from data in Pew Research source
 

Our last call out will be on the various topics and how male and female influencers post about them. The medical topics at the bottom are essentially the same but there are variations in the gendered topics. However, note that even here men talk more about female topics than male ones.

pewresearch-influencers-gendered-560
Image adapted for email from Pew Research source
 
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Read the full story from Pew Research
 
 
 
 
Healthcare Costs
Only 5.9% plan to delay health expenditures
Source: AdTaxi

AdTaxi put absolutely no methodology in their 2026 consumer spending report so we're not sure how to position it. For now we will assume there were more than 10 respondents but a survey description would be nice.

Healthcare is a Medium Level Budget Pressure
 

When asking consumers about their household budgets, groceries, gas, and housing lead the list. Mid-pack is healthcare.

adtaxi-financial-pressure-560
Image adapted for email from AdTaxi source
 
And Low on the List of Items to Delay
 

When asked which expenses they would delay or cancel, healthcare is unsurprisingly far down the list. Perhaps what is surprising is that "beauty / personal care" comes just below it. 

adtaxi-financial-delays-560
Image adapted for email from AdTaxi source
 
That Said, it's Second on List of Concerns
 

While it's not an overall high expense, it is on consumers' minds. This is likely because, as they say, everyone is a patient eventually.

adtaxi-issues-560
Image adapted for email from AdTaxi source
 
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Read the full story from AdTaxi
 
 
 
From Coverage to Activation: Designing the Commercial Systems That Win
 

Coverage may secure access, but it doesn’t guarantee treatment begins.

Klick’s latest perspective examines the operational factors that influence whether approved therapies actually translate into patient starts, sustained treatment, and stronger brand performance.

Explore why brand success requires a broader view of performance, from payer policy to workflow design and real-world adoption.

 
Read Klick's perspective now
 
 
 
AI in Health
Education is the top use of AI for health
Source: Elsevier

In a new study researchers looked at 1,695 health-related conversations and analyzed their (anonymized) content. Because of its broad definition, education took the top spot for number of conversations. 

elsevier-aihealth-number-560
Chart created from data in Elsevier source
 

The researchers also looked at the number of turns in the conversations. 

Because a small number of conversations within each category were unusually long compared to most of the dataset, the median was included to provide a more robust measure of central tendency. Most conversations consisted of two to three turns, with the minimum observed length being one turn and the maximum reaching 23 turns.

 
elsevier-aihealth-mean-560
Chart created from data in Elsevier source
 
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Read the full story from Elsevier
 
 
 
 
AI Commerce
17% of purchases expected via AI bots in five years
Source: Global Payments

A report released by Global Payments looks at consumers' opinions about purchases made via AI. The 5-year predictions are higher in 2026 than they were in 2025.

globalpayments-fiveyears-560
Image adapted for email from Global Payments source
 

These numbers are global, so if they don't match your expectations you may be in the USA. Here, the adoption is lower than in other countries and is flat year-over-year.

globalpayments-readiness-560
Image adapted for email from Global Payments source
 

Part of the continued draw for agents, regardless of the trust to allow them to buy things, is the time they can save for longer tasks (see our example, above).

globalpayments-agents-560
Image adapted for email from Global Payments source
 
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Read the full story from Global Payments
 
 
 
 
Healthcare Costs
41% of Americans say essentials to cost more
Source: ICSC

ICSC surveyed 1,003 US adults in late July to determine the resiliency of the consumer population. It found that 71% of spending is already locked in less-elastic "essentials." 29% is more discretionary. 

icsc-consumer-essentials-560
Image adapted for email from ICSC source
 

With 41% saying essentials will cost more, and 29% saying the same of nonessentials, it points to a strain on American budgets. As usual, health expenses are mostly shielded from these pressures:

icsc-consumer-budgets-560
Image adapted for email from ICSC source
 

However, it also highlights that any expenses here considered excessive will be subject to scrutiny and perhaps political action.

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Read the full story from ICSC
 
 
 
 
Market Research
19% market share for Zendesk
Source: CB Insights

CB Insights highlights that customer service is a highly fragmented market with the leader, Zendesk, only at 18.8% share.

cbinsights-customerservice-560
Image adapted for email from CB Insights source
 

This is interesting for anyone looking to connect patient support to a more traditional customer service line.

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Read the full story from CB Insights
 
 
 
 
GenAI in Healthcare
AI for checking & speed, health sites for trust
Source: Luth Research

Luth research released some teaser data from a study that combined behavioral metrics and quantitative surveys. The researchers looked at how Americans use AI for health. It's not an all-or-nothing proposition.

luth-2026-aivssites-560
Image adapted for email from Luth Research source
 

In terms of sites used, four of the seven listed can be directly controlled by pharma brands to some extent (circled in red).

luth-2026-sources-560
Image adapted for email from Luth Research source
 
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Read the full story from Luth Research
 
 
 
 
Streaming Video
Health has 2nd highest YouTube engagement rate
Source: eMarketer

YouTube is seeing engagement rates fall across the board. This would tend to be a system change as user behaviors don't change that fast. It might be larger numbers of shorts views resulting in lower engagement due to endless dopamine scroll...

emarketer-youtube-engagementrate-560
Image adapted for email from eMarketer source
 

In other news, medical health videos have the second highest level of engagement!

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Read the full story from eMarketer
 
 
 
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