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Issue 666
May 26
 
 
 
 
 
HCP Opinions
Oncologists look for innovation, patient-focus
Source: ZoomRx

ZoomRx surveyed 50 US-based oncologists and hem-oncologists to learn about their trust in the manufacturers in their specialty. When differentiating the different firms, innovation was the most important element.

zoomrx-2025-onc-features-560
Image adapted for email from ZoomRx source
 

We don't mention companies or their brands directly in the Wire. For that, jump over to the ZoomRx rankings.


Read the full story from ZoomRx
 
 
 
KH_ONESHOW-2025_R1_KLICK WIRE
 
Klick Health is the First Health Agency to Ever Win Agency of the Year
     
     

In 52 years, no health agency has ever been named Agency of the Year at The One Show. 

Until now. 

As the first independent health agency to receive this honor—and with 83 creative awards earned across Creative Week—Klick proves that world-class creativity can thrive here and raise the bar for our entire industry, without compromise.

 
Read the Press Release
 
 
 
HCP Engagement
HCPs want AI, just not from pharma
Source: CMI

CMI and Impiricus used SMS messages to survey 1,000 HCPs: physicians, NPs, PAs, and RNs (n value per FiercePharma). This survey seems to be based on a single question with text analysis used on the resultant responses.

Question: How can pharmaceutical companies better support you in making the best treatment decisions to improve patient outcomes, and what type of assistance would be most helpful?

 

We have to guess at this because the report contains no methodology information but it would explain the low values in some of the charts.

Give Me Info, Keep Your AI
 

Only 4% of HCPs mentioned AI in their responses. The majority wanted educational materials and help with financial tasks (probably including prior authorizations).

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Image adapted for email from CMI source
 
Educational Support is All About The Products
 

Breaking down the content that makes up "Educational Support" we see that it's heavily skewed towards product data.

cmi-hcp-education-topics-560
Image adapted for email from CMI source
 

There is more data in the source report and a lot of quotes from HCPs. Grab a copy and see if you agree with our theory about the methodology (CMI or Impiricus are welcome to reply and let us know as well -Ed.).


Read the full story from CMI
 
 
 
 
Reputation
US pharma and biotech down slightly re: patients
Source: PatientView

The US segment of the PatientView global patient association data shows pharma and biotech falling slightly from last year. 

patientview-2025-us-types-560
Image adapted for email from PatientView source
 

Don't worry about the year, this is the 2025 report, PatientView always uses the year the data were collected, not that the report was issued. The losses are disheartening for the US though because overall the numbers were up slightly.

patientview-2025-trend-560
Image adapted for email from PatientView source
 

You can compare these numbers to the global averages from PharmaView earlier this month.


Read the full story from PatientView
 
 
 
KH_POV_Deliverability_is_an_Evergreen_Strategy_1280
 
Is Your Email Strategy Ready for New Deliverability Rules?
     
     

Klick's latest POV, “Deliverability Is an Evergreen Strategy,” provides clear, actionable guidance on adapting to new inbox standards from Google, Yahoo!, and other ISPs. Read our perspective on how to secure inbox placement, maintain audience trust, and boost campaign performance.

Optimize your email strategy before new requirements impact your campaigns.

 
Read our perspective
 
 
 
Influencer Marketing
42% say AI is the next big thing for influencers
Source: Influencer Marketing Hub

A new report from Influencer Marketing Hub is based on interviews from 265 "experts." We put that word in quotes because the document says precious little about its methodology. We think they took written submissions and then performed text analysis on them but it's not clear.

AI Is The Next Thing for Influencer Marketing
 

When the researchers asked "What’s Next for Influencer Marketing in 2025?" AI was far and away the biggest topic.

imh-trends-560
Image adapted for email from Influencer Marketing Hub source
 
Personalization and Content Are Biggest Use Cases
 

When talking about AI, the interviewed experts really see creators acting like marketers. They can personalize content and even use AI to help create content.

imh-creators-ai-560
Image adapted for email from Influencer Marketing Hub source
 
Marketers Can Use AI to Select Creators
 

For the marketing clients of influencers, AI can help with identification, selection, and performance tracking according to the experts. This is true, but under no circumstances should marketers trust AI without double-checking its findings. Not in 2025 at least.

imh-ai-advantages-560
Image adapted for email from Influencer Marketing Hub source
 

The authors make some big claims about this report but it doesn't really deliver. The section on political polarization and the plea for creators not to be held to account for their political posts won't fly with most pharma companies. 


Read the full story from Influencer Marketing Hub
 
 
 
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Media
$34B US digital ad spend (Q4) dominated by social
Source: Pathmatics

Sensor Tower bought Pathmatics in 2021 and incorporates that platform's data into its reports. This report on Q4 2024 starts with Sensor Tower mobile data and then pivots to digital ad spend.

77% of US Digital Ad Spend Is On Social
 

This number is misleading as the Pathmatics data does not include search or retail ad revenue in its charts. We're not sure why, and search usually outperforms social by absolute numbers so it's a miss here.

That said, when comparing social to online video and display ads it dwarfs them. If YouTube was included in Video rather than Social, the numbers would change to 27.6% and 66.4%, respectively.

sensortower-2024q4-digital-560-1
Image adapted for email from Pathmatics source
 
TikTok Leads for Growth, X Shrinks
 

22% growth puts TikTok in the lead for that metric, but it is still small compared to the Meta properties. X shrank by 9% according to SensorTower. Emarketer has the platform shrinking 2.8% for the full year (not just Q4) and projects growth for 2025 so that will be interesting to track.

sensortower-2024q4-social-platforms-560
Image adapted for email from Pathmatics source
 
Health Apps #6 For In-App Purchases in US
 

Switching to mobile data, Sensor Tower's specialty, we find that Health & Fitness apps come in at #6 for in-app revenue (but #12 for downloads).

sensortower-2024q4-inapp-categories-560
Image adapted for email from Pathmatics source
 

Much of the data in this interactive report is available per country. For global marketers wanting to see differences that can be helpful.


Read the full story from Pathmatics
 
 
 
 
Office Life
Buy a good microphone to improve your charisma
Source: NPR

A study published in the Proceedings of the National Academy of Sciences looked at how poor audio quality can affect others' perception of a speaker. The researchers used real human male and female voices and then introduced audio issues similar to a low quality laptop mic.

This result is for the human male voice and asked if the person seemed hirable.

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Image adapted for email from NPR source
 

The result was a significant drop in the respondents' reactions to the lower quality audio. 


Read the full story from NPR
 
 
 
KH_GUARDRAIL_KW
 
Introducing Guardrail™
     
     

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See Guardrail in Action
 
 
 
Market Research
Social largest ad growth, retail %, search absolute
Source: eMarketer

Emarketer has a story looking at the four largest parts of the worldwide digital ad economy: search, social, streaming, and retail. We calculated the absolute increases for each channel because growth percentages are highly sensitive to the denominator.

Worldwide Growth in Channel Ad Revenue
 
emarketer-digital-ad-growth-abs-560
Image adapted for email from eMarketer source
 

Here, we can see that social got the largest absolute increase in budget while retail had the largest percentage. Meanwhile, it's important to note that search has the largest absolute amount ($54.5 billion).

Hopefully the rather cryptic headline makes sense now.


Read the full story from eMarketer
 
 
 
 
Connected TV
79% engage with CTVs, 81% have concerns
Source: Parks Associates

This report from Parks Associates seems to be a collection of data points from other studies. It contains no methodology which is a miss, but Parks Associates has been around since the 1980's so these numbers are likely well-founded.

79% of Social Video Viewers Engage
 

The primary difference between traditional TV and social video is the ability to interact with the content so it's not surprising that 8 out of 10 do so. Live video is surprisingly high on the list here.

parks-ctv-activities-560
Image adapted for email from Parks Associates source
 
81% Worry About Interactive TV
 

Data security is the top concern for users of connected TVs. Personally, I've always wondered how the lag time on CTVs is tolerated, but maybe that's just me (no personal opinions -Ed.).

parks-ctv-concerns-560
Image adapted for email from Parks Associates source
 

Read the full story from Parks Associates
 
 
 
 
AI in Healthcare
ASCO partners with Google to make guidelines "AI"
Source: ASCO

ASCO announced last week that it is releasing an AI interface for its practice guidelines. Think of it as ChatGPT but ONLY using the legitimate guidelines.

The ASCO Guidelines Assistant addresses this urgent need in oncology by providing clinicians with a solution that removes the accuracy concerns often associated with publicly available AI tools. By drawing solely from ASCO’s evidence-based, published clinical practice guidelines, the tool offers clinicians ready access to timely, trustworthy information.

 

The author isn't an oncologist so can't see the implementation, but it's likely similar to the ChatGPT tool we put in front of old Wire issues. The tool is also incorporated into the ASCO Member App.

ASCO-Guidelines-Assistant-Mobile-Mockup-560
Image adapted for email from ASCO source
 

"This partnership unlocks the value of ASCO's trusted guidelines knowledge," said ASCO CEO Clifford Hudis, MD, FACP, FASCO. "Google Cloud’s AI expertise is the engine that will drive faster access to critical information, empowering oncology professionals to make rapid, evidence-based decisions for their patients."

 

In probably-not-a-coincidence news, Microsoft has announced it is testing a new AI agent orchestrator for healthcare teams, focusing initially on tumor boards.


Read the full story from ASCO
 
 
 
 
Podcasts
Spotify playlists include illegal drug sources
Source: Ars Technica

Even two weeks after Business Insider found illegal drugs on Spotify the issue persists. We know because we searched for a well-known ADHD product and found this podcast episode:

spotify-adderall-560
Image adapted for email from Ars Technica source
 

Spotify's spokesperson told Ars that all fake podcasts flagged by the outlets were removed—considered violative as either illegal or spam content—but remained vague on whether there was any risk they might pop back up. As the service continues to play whack-a-mole, the spokesperson said, "we are constantly working to detect and remove violating content across our service."

 

Read the full story from Ars Technica
 
 
 
 
Security
Ransomware reduced in 2024 but still a problem
Source: JAMA Network

Researchers published a study of US healthcare cyberattacks in the Journal of the AMA. They show that the number of attacks and patient records affected are reduced from recent highs, they are still large.

The number of attacks reduced in 2024, likely as providers strengthened their computer systems, but are still above 2019 levels.

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Image adapted for email from JAMA Network source
 

The data volumes in these attacks continue to increase, however. So, while attacks are down, the number of patient records affected is not.

jama-cyber-records-560
Image adapted for email from JAMA Network source
 

Read the full story from JAMA Network
 
 
 
 
GenAI Search
58% of Americans have seen an AI search summary
Source: Pew Research

Pew Research tracked 2.5 million webpage visits to 1.1 million unique URLs from a group of 900 U.S. adults who agreed to share their March 2025 browsing data. 93% of these browsing histories contained AI in some way, shape, or form.

Search summaries driven by AI were particularly common with 58% seeing those.

pew-ai-webpages-560
Image adapted for email from Pew Research source
 

Most respondents found AI content as a byproduct of other activities, rather than searching for it directly.

pew-ai-terms-560
Image adapted for email from Pew Research source
 

Read the full story from Pew Research
 
 
 
 
Generative AI
Ask your doctor if Puppramin is right for you
Source: YouTube

This is issue #666 of the Wire and this is story #13... so we have to make it extra evil (please, just don't -Ed.). Last week a filmmaker, PJ Ace, posted an AI-generated ad for Puppramin and it is evilly hilarious. Also, extremely high quality for text-to-video.

puppramin-collage-560
Image adapted for email from YouTube source
 

We bet you can't just watch it once.

And for anyone craving a more authentic 666 reference, here is Iron Maiden with the title track from their 1982 album The Number of the Beast to end with some classic metal (ok fine, but you owe me -Ed.).


Read the full story from YouTube
 
 
 
 
 
 
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